Magnifying Endoscopic Findings Can Predict Clinical Outcome during Long-Term Follow-Up of More Than 12 Months in Patients with Ulcerative Colitis
Joint Authors
Nakayama, Toshiyuki
Shiota, Junya
Matsushima, Kayoko
Hayashi, Tomayoshi
Takeshima, Fuminao
Nakao, Kazuhiko
Uehara, Ryohei
Chen, Chun Chuan
Isomoto, Hajime
Source
Gastroenterology Research and Practice
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-02
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background and Aims.
To explore the association of magnifying endoscopic (ME) findings with histopathology and relapse in ulcerative colitis (UC).
Methods.
Forty-six patients with UC underwent ME with narrow band imaging (NBI) and crystal violet staining and were followed for more than 12 months.
ME findings with vital staining were classified into ME-A, regular arrangement of round to oval pits; ME-B, irregular arrangement with/without enlarged spaces between even pits; ME-C, irregular pits in size and shape with more irregular arrangement of pits; and ME-D, disrupted or disappeared pits.
NBI-guided ME features of microvascular pattern (MVP) were divided into the MVP-regular and MVP-irregular type.
Results.
There were 5, 24, 10, and 7 cases of ME-A, ME-B, ME-C, and ME-D grade, respectively, while there were 21 and 25 of MVP-regular and MVP-irregular type, respectively.
ME classifications were significantly associated with Matts endoscopic grade.
ME classifications and MVP types were significantly associated with each pathognomonic microscopic feature of severe mucosal inflammation, crypt abscess, and goblet cell depletion.
There were significant differences in the percentages of remission among ME classifications and between MVP types.
Conclusion.
ME findings can be predictive of relapse in UC and reliable for in vivo histopathological assessment.
American Psychological Association (APA)
Isomoto, Hajime& Uehara, Ryohei& Hayashi, Tomayoshi& Shiota, Junya& Matsushima, Kayoko& Chen, Chun Chuan…[et al.]. 2013. Magnifying Endoscopic Findings Can Predict Clinical Outcome during Long-Term Follow-Up of More Than 12 Months in Patients with Ulcerative Colitis. Gastroenterology Research and Practice،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-489212
Modern Language Association (MLA)
Isomoto, Hajime…[et al.]. Magnifying Endoscopic Findings Can Predict Clinical Outcome during Long-Term Follow-Up of More Than 12 Months in Patients with Ulcerative Colitis. Gastroenterology Research and Practice No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-489212
American Medical Association (AMA)
Isomoto, Hajime& Uehara, Ryohei& Hayashi, Tomayoshi& Shiota, Junya& Matsushima, Kayoko& Chen, Chun Chuan…[et al.]. Magnifying Endoscopic Findings Can Predict Clinical Outcome during Long-Term Follow-Up of More Than 12 Months in Patients with Ulcerative Colitis. Gastroenterology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-489212
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-489212