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Prevalence of Transfusion Transmitted Virus Infection in Hemodialysis Patients and Injection Drug Users Compared to Healthy Blood Donors in Isfahan, Iran
Joint Authors
Javadi, Abbas-Ali
Yazdani, Mohammad Reza
Khorvash, Farzin
Emami Naeini, Alireza
Ataei, Behrooz
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-19
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Introduction.
The pathogenicity and transmission routes of Transfusion Transmitted Virus (TTV) remain unclear.
The aim of this study was to determine the prevalence of TTV in hemodialysis patients, injecting drug users (IDUs), and healthy blood donors, in Isfahan, Iran.
Method.
In a case-control study, a total of 108 subjects were put into three groups namely Group I, 36 hemodialysis patients; Group II, 36 IDUs; and Group III, 36 healthy blood donors as the control group.
A 5 ml blood sample was collected from each subject in an EDTA-containing tube.
Samples were tested for TTV DNA by means of real-time polymerase chain reaction (PCR).
Results.
The mean age was 38.7±14.7 years.
Seventy-one subjects (66%) were male.
Of the108 cases, 30 (27.8%) were TTV positive and 78 (72.2%) were TTV negative.
The prevalence of TTV in IDUs [21 (58%)] was significantly higher than in the other groups [group I: 6 (17 %) and group III: 3 (8%)] (P<0.0001).
Conclusion.
The prevalence of TTV in IDUs is significantly higher than in both hemodialysis patients and general population in Isfahan, Iran.
It seems necessary to take serious measures to reduce the risk of TTV transmission to IDUs’ close contacts and health care providers.
American Psychological Association (APA)
Ataei, Behrooz& Emami Naeini, Alireza& Khorvash, Farzin& Yazdani, Mohammad Reza& Javadi, Abbas-Ali. 2012. Prevalence of Transfusion Transmitted Virus Infection in Hemodialysis Patients and Injection Drug Users Compared to Healthy Blood Donors in Isfahan, Iran. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-489245
Modern Language Association (MLA)
Ataei, Behrooz…[et al.]. Prevalence of Transfusion Transmitted Virus Infection in Hemodialysis Patients and Injection Drug Users Compared to Healthy Blood Donors in Isfahan, Iran. Gastroenterology Research and Practice No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-489245
American Medical Association (AMA)
Ataei, Behrooz& Emami Naeini, Alireza& Khorvash, Farzin& Yazdani, Mohammad Reza& Javadi, Abbas-Ali. Prevalence of Transfusion Transmitted Virus Infection in Hemodialysis Patients and Injection Drug Users Compared to Healthy Blood Donors in Isfahan, Iran. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-489245
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-489245