Verbal Episodic Memory and Endogenous Estradiol : An Association in Patients with Mild Cognitive Impairment and Alzheimer's Disease
Joint Authors
Bittner, V.
Riepe, Matthias W.
Bittner, D. M.
Source
Current Gerontology and Geriatrics Research
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-19
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
In the continuum of patients with Alzheimer's disease (AD), mild cognitive impairment (MCI), and normal controls, a possible association of verbal memory and endogenous estradiol (E2) levels was investigated.
Verbal episodic memory was measured with a german version of the California verbal memory test (CVLT).
Results were controlled for apolipoprotein E (ApoE) phenotype.
We studied 37 controls, 32 MCIs and 117 ADs.
Groups differed in all trials of the CVLT (P<0.001) and in E2 levels (P<0.001).
E2 levels differed significantly between groups only among females (P<0.001).
In females correcting for age and ApoE, there was an overall correlation between CVLT delayed recall and level of E2 (P=0.025).
Stepwise regression analyses found E2 level to be a significant predictor for CVLT delayed recall (P<0.001).
It may be concluded that lower E2 levels occur more in the course of the disease than may be considered as a risk factor per se.
American Psychological Association (APA)
Bittner, D. M.& Bittner, V.& Riepe, Matthias W.. 2011. Verbal Episodic Memory and Endogenous Estradiol : An Association in Patients with Mild Cognitive Impairment and Alzheimer's Disease. Current Gerontology and Geriatrics Research،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-489348
Modern Language Association (MLA)
Bittner, D. M.…[et al.]. Verbal Episodic Memory and Endogenous Estradiol : An Association in Patients with Mild Cognitive Impairment and Alzheimer's Disease. Current Gerontology and Geriatrics Research No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-489348
American Medical Association (AMA)
Bittner, D. M.& Bittner, V.& Riepe, Matthias W.. Verbal Episodic Memory and Endogenous Estradiol : An Association in Patients with Mild Cognitive Impairment and Alzheimer's Disease. Current Gerontology and Geriatrics Research. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-489348
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-489348