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Bio-Prospecting of a Few Brown Seaweeds for Their Cytotoxic and Antioxidant Activities
Joint Authors
Sabu, A. S.
Vinayak, Rashmi C.
Chatterji, Anil
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Methanolic extracts (MEs) of seven brown seaweeds occurring in the Indian coastal waters were screened for their cytotoxic and antioxidant properties following various assays.
The methanolic extracts of seaweeds in the order of Dictyopteris australis > Spatoglossum variabile > Stoechospermum marginatum > Spatoglossum aspermum showed significant cytotoxic activity.
A very high DPPH radical scavenging activity was exhibited by the methanolic extracts prepared from St.
marginatum, Padina tetrastromatica, Dictyopteris delicatula and S.
aspermum.
The total phenolic content of the MEs varied from 13.19 ± 0.32 to 25.29 ± 0.445 gallic acid equivalents (mg g−1 of methanolic extract).
The reducing power assay indicated a dose dependency, at concentrations of 0.1, 0.5 and 1.0 and 2.0 mg mL−1 of MEs and decreased in the following order: Butylated hydroxy toluene > P.
tetrastromatica > D.
delicatula > S.
aspermum > S.
variabile > S.
marginatum > D.
australis > S.
marginatum.
Furthermore, D.
australis, S.
aspermum, S.
variabile and S.
marginatum demonstrated good metal ion chelating properties.
All the above evidences suggest that, the antioxidant compounds found in brown seaweeds scavenge free radicals through effective intervention.
This decisively promotes them as a potential source of natural antioxidants.
American Psychological Association (APA)
Vinayak, Rashmi C.& Sabu, A. S.& Chatterji, Anil. 2011. Bio-Prospecting of a Few Brown Seaweeds for Their Cytotoxic and Antioxidant Activities. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-489360
Modern Language Association (MLA)
Vinayak, Rashmi C.…[et al.]. Bio-Prospecting of a Few Brown Seaweeds for Their Cytotoxic and Antioxidant Activities. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-489360
American Medical Association (AMA)
Vinayak, Rashmi C.& Sabu, A. S.& Chatterji, Anil. Bio-Prospecting of a Few Brown Seaweeds for Their Cytotoxic and Antioxidant Activities. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-489360
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-489360