Antimicrobial Peptides : Versatile Biological Properties
Joint Authors
Pushpanathan, Muthuirulan
Rajendhran, Jeyaprakash
Paramasamy, Gunasekaran
Source
International Journal of Peptides
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-26
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Antimicrobial peptides are diverse group of biologically active molecules with multidimensional properties.
In recent past, a wide variety of AMPs with diverse structures have been reported from different sources such as plants, animals, mammals, and microorganisms.
The presence of unusual amino acids and structural motifs in AMPs confers unique structural properties to the peptide that attribute for their specific mode of action.
The ability of these active AMPs to act as multifunctional effector molecules such as signalling molecule, immune modulators, mitogen, antitumor, and contraceptive agent makes it an interesting candidate to study every aspect of their structural and biological properties for prophylactic and therapeutic applications.
In addition, easy cloning and recombinant expression of AMPs in heterologous plant host systems provided a pipeline for production of disease resistant transgenic plants.
Besides these properties, AMPs were also used as drug delivery vectors to deliver cell impermeable drugs to cell interior.
The present review focuses on the diversity and broad spectrum antimicrobial activity of AMPs along with its multidimensional properties that could be exploited for the application of these bioactive peptides as a potential and promising drug candidate in pharmaceutical industries.
American Psychological Association (APA)
Pushpanathan, Muthuirulan& Paramasamy, Gunasekaran& Rajendhran, Jeyaprakash. 2013. Antimicrobial Peptides : Versatile Biological Properties. International Journal of Peptides،Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-489590
Modern Language Association (MLA)
Pushpanathan, Muthuirulan…[et al.]. Antimicrobial Peptides : Versatile Biological Properties. International Journal of Peptides No. 2013 (2013), pp.1-15.
https://search.emarefa.net/detail/BIM-489590
American Medical Association (AMA)
Pushpanathan, Muthuirulan& Paramasamy, Gunasekaran& Rajendhran, Jeyaprakash. Antimicrobial Peptides : Versatile Biological Properties. International Journal of Peptides. 2013. Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-489590
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-489590