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Adult Nephroblastoma with Predominant Epithelial Component : A Differential Diagnostic Candidate of Papillary Renal Cell Carcinoma and Metanephric Adenoma—Report of Three Cases
Joint Authors
Watanabe, Shiho
Nihei, Naoki
Matsushima, Jun
Nagashima, Yoji
Mikami, Shuji
Kuroda, Naoto
Ota, Satoshi
Murata, Shin-ichi
Nakatani, Yukio
Shimizu, Michio
Naganuma, Hiroshi
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-03
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Although nephroblastoma is the commonest renal tumor of childhood, it is rare in adults.
In cases of predominantly epithelial type occurring in adulthood, it might be difficult to distinguish it from papillary renal cell carcinoma and metanephric adenoma.
Here, we report three cases of adult epithelial nephroblastoma in 24-, 76-, and 21-year-old females.
Histologically, the tumors were composed of papillotubular architectures of small and uniform tumor cells with high nucleocytoplasmic ratio without blastemal element.
Immunohistochemically, the tumor cells were positive for WT-1 and CD57 but negative for AMACR, which was helpful to exclude the possibility of papillary renal cell carcinoma.
Metanephric adenoma is a benign tumor, which can be distinguished by the observation of the cellular atypism and growth pattern.
However, nephroblastoma with predominant epithelial element mimics the malignant counterpart of metanephric adenoma, that is, “metanephric adenocarcinoma.”
American Psychological Association (APA)
Watanabe, Shiho& Naganuma, Hiroshi& Shimizu, Michio& Ota, Satoshi& Murata, Shin-ichi& Nihei, Naoki…[et al.]. 2013. Adult Nephroblastoma with Predominant Epithelial Component : A Differential Diagnostic Candidate of Papillary Renal Cell Carcinoma and Metanephric Adenoma—Report of Three Cases. Case Reports in Pathology،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-489625
Modern Language Association (MLA)
Watanabe, Shiho…[et al.]. Adult Nephroblastoma with Predominant Epithelial Component : A Differential Diagnostic Candidate of Papillary Renal Cell Carcinoma and Metanephric Adenoma—Report of Three Cases. Case Reports in Pathology No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-489625
American Medical Association (AMA)
Watanabe, Shiho& Naganuma, Hiroshi& Shimizu, Michio& Ota, Satoshi& Murata, Shin-ichi& Nihei, Naoki…[et al.]. Adult Nephroblastoma with Predominant Epithelial Component : A Differential Diagnostic Candidate of Papillary Renal Cell Carcinoma and Metanephric Adenoma—Report of Three Cases. Case Reports in Pathology. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-489625
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-489625