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Add-On Effect of Chinese Herbal Medicine on Mortality in Myocardial Infarction : Systematic Review and Meta-Analysis of Randomized Controlled Trials
Joint Authors
Mao, Chen
Tang, Jin Ling
Ziea, Eric T. C.
Wu, Xin Yin
Wong, Vivian C. W.
Ying, Qin
Ma, Polly H. X.
Chung, Vincent Chi-Ho
Tam, Wilson W. S.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-10
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
In China, Chinese herbal medicine (CHM) is widely used as an adjunct to biomedicine (BM) in treating myocardial infarction (MI).
This meta-analysis of RCTs evaluated the efficacy of combined CHM-BM in the treatment of MI, compared to BM alone.
Sixty-five RCTs (12,022 patients) of moderate quality were identified.
6,036 patients were given CHM plus BM, and 5,986 patients used BM only.
Combined results showed clear additional effect of CHM-BM treatment in reducing all-cause mortality (relative risk reduction (RRR) = 37%, 95% CI = 28%–45%, I2=0.0%) and mortality of cardiac origin (RRR = 39%, 95% CI = 22%–52%, I2=22.8).
Benefits remained after random-effect trim and fill adjustment for publication bias (adjusted RRR for all-cause mortality = 29%, 95% CI = 16%–40%; adjusted RRR for cardiac death = 32%, 95% CI = 15%–46%).
CHM is also found to be efficacious in lowering the risk of fatal and nonfatal cardiogenic shock, cardiac arrhythmia, myocardial reinfarction, heart failure, angina, and occurrence of total heart events.
In conclusion, addition of CHM is very likely to be able to improve survival of MI patients who are already receiving BM.
Further confirmatory evaluation via large blinded randomized trials is warranted.
American Psychological Association (APA)
Chung, Vincent Chi-Ho& Mao, Chen& Ying, Qin& Tam, Wilson W. S.& Wu, Xin Yin& Ma, Polly H. X.…[et al.]. 2013. Add-On Effect of Chinese Herbal Medicine on Mortality in Myocardial Infarction : Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-489626
Modern Language Association (MLA)
Chung, Vincent Chi-Ho…[et al.]. Add-On Effect of Chinese Herbal Medicine on Mortality in Myocardial Infarction : Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-489626
American Medical Association (AMA)
Chung, Vincent Chi-Ho& Mao, Chen& Ying, Qin& Tam, Wilson W. S.& Wu, Xin Yin& Ma, Polly H. X.…[et al.]. Add-On Effect of Chinese Herbal Medicine on Mortality in Myocardial Infarction : Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-489626
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-489626