ITOPoly(Aniline)Sol-Gel Glass : An Optically Transparent, pH-Responsive Substrate for Supported Lipid Bilayers
Joint Authors
al-Obeidi, Ahmed
Saavedra, S. Scott
Orosz, Kristina S.
Ge, Chenhao
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Materials Science , Minerals
Civil Engineering
Abstract EN
Described here is fabrication of a pH-sensitive, optically transparent transducer composed of a planar indium-tin oxide (ITO) electrode overcoated with a poly(aniline) (PANI) thin film and a porous sol-gel layer.
Adsorption of the PANI film renders the ITO electrode sensitive to pH, whereas the sol-gel spin-coated layer makes the upper surface compatible with fusion of phospholipid vesicles to form a planar supported lipid bilayer (PSLB).
The response to changes in the pH of the buffer contacting the sol-gel/PANI/ITO electrode is pseudo-Nernstian with a slope of 52 mV/pH over a pH range of 4–9.
Vesicle fusion forms a laterally continuous PSLB on the upper sol-gel surface that is fluid with a lateral lipid diffusion coefficient of 2.2 μm2/s measured by fluorescence recovery after photobleaching.
Due to its lateral continuity and lack of defects, the PSLB blocks the pH response of the underlying electrode to changes in the pH of the overlying buffer.
This architecture is simpler to fabricate than previously reported ITO electrodes derivatized for PSLB formation and should be useful for optical monitoring of proton transport across supported membranes derivatized with ionophores and ion channels.
American Psychological Association (APA)
al-Obeidi, Ahmed& Ge, Chenhao& Orosz, Kristina S.& Saavedra, S. Scott. 2013. ITOPoly(Aniline)Sol-Gel Glass : An Optically Transparent, pH-Responsive Substrate for Supported Lipid Bilayers. Journal of Materials،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-489714
Modern Language Association (MLA)
al-Obeidi, Ahmed…[et al.]. ITOPoly(Aniline)Sol-Gel Glass : An Optically Transparent, pH-Responsive Substrate for Supported Lipid Bilayers. Journal of Materials No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-489714
American Medical Association (AMA)
al-Obeidi, Ahmed& Ge, Chenhao& Orosz, Kristina S.& Saavedra, S. Scott. ITOPoly(Aniline)Sol-Gel Glass : An Optically Transparent, pH-Responsive Substrate for Supported Lipid Bilayers. Journal of Materials. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-489714
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-489714