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Non-Invasive Radiofrequency-Induced Targeted Hyperthermia for the Treatment of Hepatocellular Carcinoma
Joint Authors
Raoof, Mustafa
Curley, Steven A.
Source
International Journal of Hepatology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Targeted biological therapies for hepatocellular cancer have shown minimal improvements in median survival.
Multiple pathways to oncogenesis leading to rapid development of resistance to such therapies is a concern.
Non-invasive radiofrequency field-induced targeted hyperthermia using nanoparticles is a radical departure from conventional modalities.
In this paper we underscore the need for innovative strategies for the treatment of hepatocellular cancer, describe the central paradigm of targeted hyperthermia using non-invasive electromagnetic energy, review the process of characterization and modification of nanoparticles for the task, and summarize data from cell-based and animal-based models of hepatocellular cancer treated with non-invasive RF energy.
Finally, future strategies and challenges in bringing this modality from bench to clinic are discussed.
American Psychological Association (APA)
Raoof, Mustafa& Curley, Steven A.. 2011. Non-Invasive Radiofrequency-Induced Targeted Hyperthermia for the Treatment of Hepatocellular Carcinoma. International Journal of Hepatology،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-489719
Modern Language Association (MLA)
Raoof, Mustafa& Curley, Steven A.. Non-Invasive Radiofrequency-Induced Targeted Hyperthermia for the Treatment of Hepatocellular Carcinoma. International Journal of Hepatology No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-489719
American Medical Association (AMA)
Raoof, Mustafa& Curley, Steven A.. Non-Invasive Radiofrequency-Induced Targeted Hyperthermia for the Treatment of Hepatocellular Carcinoma. International Journal of Hepatology. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-489719
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-489719