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Methotrexate Induced Pancytopenia
Joint Authors
Gonzalez-Ibarra, Fernando
Badin, Simon
Elamir, Mazhar
Eivaz-Mohammadi, Sahar
Surapaneni, Shiri
Alsaadi, Hazem
Marian, Valentin
Syed, Amer K.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-05
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The well-reported methotrexate (MTX) toxicities are based on the duration and cumulative dosing of drug.
The typical toxicities can be predicted by the timing of drug administration, where mucositis occurs as an earlier effect, while myelosuppression and the sequelae of pancytopenia occur later after MTX administration.
Despite these well-known toxicities, low dose MTX therapy can become problematic, in particular with the elderly, who are at a greater risk for significant myelosuppression.
We present a case of a 73-year-old female with pancytopenia causing severe neutropenia, mucocutaneous bleeding, and bruising and requiring intravenous antibiotic therapy and limited transfusion dependence as a result of low dose daily MTX for rheumatoid arthritis.
American Psychological Association (APA)
Gonzalez-Ibarra, Fernando& Eivaz-Mohammadi, Sahar& Surapaneni, Shiri& Alsaadi, Hazem& Syed, Amer K.& Badin, Simon…[et al.]. 2014. Methotrexate Induced Pancytopenia. Case Reports in Rheumatology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-489894
Modern Language Association (MLA)
Gonzalez-Ibarra, Fernando…[et al.]. Methotrexate Induced Pancytopenia. Case Reports in Rheumatology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-489894
American Medical Association (AMA)
Gonzalez-Ibarra, Fernando& Eivaz-Mohammadi, Sahar& Surapaneni, Shiri& Alsaadi, Hazem& Syed, Amer K.& Badin, Simon…[et al.]. Methotrexate Induced Pancytopenia. Case Reports in Rheumatology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-489894
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-489894