Role of HLA in Hematopoietic Stem Cell Transplantation
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-02
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The selection of hematopoietic stem cell transplantation (HSCT) donors includes a rigorous assessment of the availability and human leukocyte antigen (HLA) match status of donors.
HLA plays a critical role in HSCT, but its involvement in HSCT is constantly in flux because of changing technologies and variations in clinical transplantation results.
The increased availability of HSCT through the use of HLA-mismatched related and unrelated donors is feasible with a more complete understanding of permissible HLA mismatches and the role of killer-cell immunoglobulin-like receptor (KIR) genes in HSCT.
The influence of nongenetic factors on the tolerability of HLA mismatching has recently become evident, demonstrating a need for the integration of both genetic and nongenetic variables in donor selection.
American Psychological Association (APA)
Park, Meerim& Seo, Jong Jin. 2012. Role of HLA in Hematopoietic Stem Cell Transplantation. Bone Marrow Research،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-490015
Modern Language Association (MLA)
Park, Meerim& Seo, Jong Jin. Role of HLA in Hematopoietic Stem Cell Transplantation. Bone Marrow Research No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-490015
American Medical Association (AMA)
Park, Meerim& Seo, Jong Jin. Role of HLA in Hematopoietic Stem Cell Transplantation. Bone Marrow Research. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-490015
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490015