Role of HLA in Hematopoietic Stem Cell Transplantation

Joint Authors

Park, Meerim
Seo, Jong Jin

Source

Bone Marrow Research

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2012-10-02

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Biology

Abstract EN

The selection of hematopoietic stem cell transplantation (HSCT) donors includes a rigorous assessment of the availability and human leukocyte antigen (HLA) match status of donors.

HLA plays a critical role in HSCT, but its involvement in HSCT is constantly in flux because of changing technologies and variations in clinical transplantation results.

The increased availability of HSCT through the use of HLA-mismatched related and unrelated donors is feasible with a more complete understanding of permissible HLA mismatches and the role of killer-cell immunoglobulin-like receptor (KIR) genes in HSCT.

The influence of nongenetic factors on the tolerability of HLA mismatching has recently become evident, demonstrating a need for the integration of both genetic and nongenetic variables in donor selection.

American Psychological Association (APA)

Park, Meerim& Seo, Jong Jin. 2012. Role of HLA in Hematopoietic Stem Cell Transplantation. Bone Marrow Research،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-490015

Modern Language Association (MLA)

Park, Meerim& Seo, Jong Jin. Role of HLA in Hematopoietic Stem Cell Transplantation. Bone Marrow Research No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-490015

American Medical Association (AMA)

Park, Meerim& Seo, Jong Jin. Role of HLA in Hematopoietic Stem Cell Transplantation. Bone Marrow Research. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-490015

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-490015