The Interaction Pattern between a Homology Model of 40S Ribosomal S9 Protein of Rhizoctonia solani and 1-Hydroxyphenaize by Docking Study
Joint Authors
Sanchita,
Samad, Abdul
Patra, Dharani Dhar
Dharni, Seema
Sharma, Ashok
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
1-Hydroxyphenazine (1-OH-PHZ), a natural product from Pseudomonas aeruginosa strain SD12, was earlier reported to have potent antifungal activity against Rhizoctonia solani.
In the present work, the antifungal activity of 1-OH-PHZ on 40S ribosomal S9 protein was validated by molecular docking approach.
1-OH-PHZ showed interaction with two polar contacts with residues, Arg69 and Phe19, which inhibits the synthesis of fungal protein.
Our study reveals that 1-OH-PHZ can be a potent inhibitor of 40S ribosomal S9 protein of R.
solani that may be a promising approach for the management of fungal diseases.
American Psychological Association (APA)
Dharni, Seema& Sanchita, & Samad, Abdul& Sharma, Ashok& Patra, Dharani Dhar. 2014. The Interaction Pattern between a Homology Model of 40S Ribosomal S9 Protein of Rhizoctonia solani and 1-Hydroxyphenaize by Docking Study. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-490206
Modern Language Association (MLA)
Dharni, Seema…[et al.]. The Interaction Pattern between a Homology Model of 40S Ribosomal S9 Protein of Rhizoctonia solani and 1-Hydroxyphenaize by Docking Study. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-490206
American Medical Association (AMA)
Dharni, Seema& Sanchita, & Samad, Abdul& Sharma, Ashok& Patra, Dharani Dhar. The Interaction Pattern between a Homology Model of 40S Ribosomal S9 Protein of Rhizoctonia solani and 1-Hydroxyphenaize by Docking Study. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-490206
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490206
