Splitting Strategy for Simulating Genetic Regulatory Networks

Joint Authors

Liu, Xueping
You, Xiong
Musa, Ibrahim Hussein

Source

Computational and Mathematical Methods in Medicine

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-02-02

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Medicine

Abstract EN

The splitting approach is developed for the numerical simulation of genetic regulatory networks with a stable steady-state structure.

The numerical results of the simulation of a one-gene network, a two-gene network, and a p53-mdm2 network show that the new splitting methods constructed in this paper are remarkably more effective and more suitable for long-term computation with large steps than the traditional general-purpose Runge-Kutta methods.

The new methods have no restriction on the choice of stepsize due to their infinitely large stability regions.

American Psychological Association (APA)

You, Xiong& Liu, Xueping& Musa, Ibrahim Hussein. 2014. Splitting Strategy for Simulating Genetic Regulatory Networks. Computational and Mathematical Methods in Medicine،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-490240

Modern Language Association (MLA)

You, Xiong…[et al.]. Splitting Strategy for Simulating Genetic Regulatory Networks. Computational and Mathematical Methods in Medicine No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-490240

American Medical Association (AMA)

You, Xiong& Liu, Xueping& Musa, Ibrahim Hussein. Splitting Strategy for Simulating Genetic Regulatory Networks. Computational and Mathematical Methods in Medicine. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-490240

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-490240