Developmental Mechanisms in Articular Cartilage Degradation in Osteoarthritis
Author
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-29
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Osteoarthritis is the most common arthritic condition, which involves progressive degeneration of articular cartilage.
The most recent accomplishments have significantly advanced our understanding on the mechanisms of the disease development and progression.
The most intriguing is the growing evidence indicating that extracellular matrix destruction in osteoarthritic articular cartilage resembles that in the hypertrophic zone of fetal growth plate during endochondral ossification.
This suggests common regulatory mechanisms of matrix degradation in OA and in the development and can provide new approaches for the treatment of the disease by targeting reparation of chondrocyte phenotype.
American Psychological Association (APA)
Tchetina, Elena V.. 2010. Developmental Mechanisms in Articular Cartilage Degradation in Osteoarthritis. Arthritis،Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-490297
Modern Language Association (MLA)
Tchetina, Elena V.. Developmental Mechanisms in Articular Cartilage Degradation in Osteoarthritis. Arthritis No. 2011 (2011), pp.1-16.
https://search.emarefa.net/detail/BIM-490297
American Medical Association (AMA)
Tchetina, Elena V.. Developmental Mechanisms in Articular Cartilage Degradation in Osteoarthritis. Arthritis. 2010. Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-490297
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490297