![](/images/graphics-bg.png)
Symptomatic Hypoglycemia Related to Inappropriately High IGF-II Serum Levels in a Patient with Desmoplastic Small Round Cell Tumor
Joint Authors
Castro, Gilberto
Hoff, Paulo M.
Barra, Williams Fernandes
Hoff, Ana Oliveira
Siqueira, Sheila A. C.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-02
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
A 45-year old man was diagnosed with desmoplastic small round cell tumor (DSRCT) with involvement of the peritoneum and pelvis.
Disease progression was observed despite systemic chemotherapy.
Six months after diagnosis, he developed severe hypoglycemia presented with seizures.
He received intravenous glucose infusion and hydrocortisone with poor glycemic control, but with seizures resolution.
The investigation excluded insulinoma, adrenal, liver and GH deficiencies.
Laboratory showed slight rise of IGF-II and significant increase of the ratio IGF-II : IGF-I, which is pathognomonic of non-islet cell tumor hypoglycemia (NICTH).
He received the diagnoses of NICTH related to IGF-II inappropriate production by DSRCT.
Despite the attempt to control tumor mass and hypoglycemia, the patient died 9 months after diagnosis.
NICTH related to inappropriate IGF-II secretion should be investigated in all cancer patients with refractory hypoglycemia whom insulinoma and other metabolic abnormalities were excluded from.
American Psychological Association (APA)
Barra, Williams Fernandes& Castro, Gilberto& Hoff, Ana Oliveira& Siqueira, Sheila A. C.& Hoff, Paulo M.. 2010. Symptomatic Hypoglycemia Related to Inappropriately High IGF-II Serum Levels in a Patient with Desmoplastic Small Round Cell Tumor. Case Reports in Medicine،Vol. 2010, no. 2010, pp.1-3.
https://search.emarefa.net/detail/BIM-490310
Modern Language Association (MLA)
Barra, Williams Fernandes…[et al.]. Symptomatic Hypoglycemia Related to Inappropriately High IGF-II Serum Levels in a Patient with Desmoplastic Small Round Cell Tumor. Case Reports in Medicine No. 2010 (2010), pp.1-3.
https://search.emarefa.net/detail/BIM-490310
American Medical Association (AMA)
Barra, Williams Fernandes& Castro, Gilberto& Hoff, Ana Oliveira& Siqueira, Sheila A. C.& Hoff, Paulo M.. Symptomatic Hypoglycemia Related to Inappropriately High IGF-II Serum Levels in a Patient with Desmoplastic Small Round Cell Tumor. Case Reports in Medicine. 2010. Vol. 2010, no. 2010, pp.1-3.
https://search.emarefa.net/detail/BIM-490310
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490310