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From Structure to Catalysis : Recent Developments in the Biotechnological Applications of Lipases
Joint Authors
Moura, Marcelo V.
Anobom, Cristiane D.
Andrade, Guilherme C.
Pinheiro, Anderson S.
Aguieiras, Erika C. G.
Freire, Denise Maria Guimarães
De-Andrade, Rafael A.
Almeida, Rodrigo Volcan
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-24
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Microbial lipases are highly appreciated as biocatalysts due to their peculiar characteristics such as the ability to utilize a wide range of substrates, high activity and stability in organic solvents, and regio- and/or enantioselectivity.
These enzymes are currently being applied in a variety of biotechnological processes, including detergent preparation, cosmetics and paper production, food processing, biodiesel and biopolymer synthesis, and the biocatalytic resolution of pharmaceutical derivatives, esters, and amino acids.
However, in certain segments of industry, the use of lipases is still limited by their high cost.
Thus, there is a great interest in obtaining low-cost, highly active, and stable lipases that can be applied in several different industrial branches.
Currently, the design of specific enzymes for each type of process has been used as an important tool to address the limitations of natural enzymes.
Nowadays, it is possible to “order” a “customized” enzyme that has ideal properties for the development of the desired bioprocess.
This review aims to compile recent advances in the biotechnological application of lipases focusing on various methods of enzyme improvement, such as protein engineering (directed evolution and rational design), as well as the use of structural data for rational modification of lipases in order to create higher active and selective biocatalysts.
American Psychological Association (APA)
Anobom, Cristiane D.& Pinheiro, Anderson S.& De-Andrade, Rafael A.& Aguieiras, Erika C. G.& Andrade, Guilherme C.& Moura, Marcelo V.…[et al.]. 2014. From Structure to Catalysis : Recent Developments in the Biotechnological Applications of Lipases. BioMed Research International،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-490355
Modern Language Association (MLA)
Anobom, Cristiane D.…[et al.]. From Structure to Catalysis : Recent Developments in the Biotechnological Applications of Lipases. BioMed Research International No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-490355
American Medical Association (AMA)
Anobom, Cristiane D.& Pinheiro, Anderson S.& De-Andrade, Rafael A.& Aguieiras, Erika C. G.& Andrade, Guilherme C.& Moura, Marcelo V.…[et al.]. From Structure to Catalysis : Recent Developments in the Biotechnological Applications of Lipases. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-490355
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490355