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Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography
Joint Authors
Fujimoto, James G.
Schmitt, Joseph M.
Tsai, Tsung-Han
Lee, Hsiang-Chieh
Huang, Qin
Mashimo, Hiroshi
Tao, Yuankai K.
Ahsen, Osman O.
Zhou, Chao
Figueiredo, Marisa
Adler, Desmond C.
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Two main nonsurgical endoscopic approaches for ablating dysplastic and early cancer lesions in the esophagus have gained popularity, namely, radiofrequency ablation (RFA) and cryospray ablation (CSA).
We report a uniquely suited endoscopic and near-microscopic imaging modality, three-dimensional (3D) optical coherence tomography (OCT), to assess and compare the esophagus immediately after RFA and CSA.
The maximum depths of architectural changes were measured and compared between the two treatment groups.
RFA was observed to induce 230~260 μm depth of architectural changes after each set of ablations over a particular region, while CSA was observed to induce edema-like spongiform changes to ~640 μm depth within the ablated field.
The ability to obtain micron-scale depth-resolved images of tissue structural changes following different ablation therapies makes 3D-OCT an ideal tool to assess treatment efficacy.
Such information could be potentially used to provide real-time feedback for treatment dosing and to identify regions that need further retreatment.
American Psychological Association (APA)
Tsai, Tsung-Han& Zhou, Chao& Lee, Hsiang-Chieh& Tao, Yuankai K.& Ahsen, Osman O.& Figueiredo, Marisa…[et al.]. 2012. Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-490391
Modern Language Association (MLA)
Tsai, Tsung-Han…[et al.]. Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography. Gastroenterology Research and Practice No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-490391
American Medical Association (AMA)
Tsai, Tsung-Han& Zhou, Chao& Lee, Hsiang-Chieh& Tao, Yuankai K.& Ahsen, Osman O.& Figueiredo, Marisa…[et al.]. Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-490391
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490391