Structural Configuration of Myelin Figures Using Fluorescence Microscopy
Joint Authors
Vashaee, Daryoosh
Mozafari, Masoud
Tayebi, Lobat
Parikh, Atul N.
Source
International Journal of Photoenergy
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Using epifluorescence microscopy, the configuration of myelin figures that are formed upon hydration of lipid stack was studied qualitatively.
Little knowledge is currently available for conditions that determine the diameter of myelin figures and their degree of multilamellarity.
Examining more than 300 samples, we realized that there are distinct populations of myelin figures protruding from discrete regions of lipid stack.
Each population contains myelin figures with similar diameters.
This indicates a direct relationship between local characteristics of parent lipid stack and the diameter of myelin figures.
Evidenced by fluorescent images, we classified all the observed myelin figures into three major groups of (1) solid tubes, (2) thin tethers, and (3) hollow tubes.
Solid tubes are the most common structure of myelin figures which appeared as dense shiny cylinders.
Thin tethers, with long hair-shaped structure, were observed protruding from part of lipid plaque which is likely to be under tension.
Hollow tubes were protruded from the parts that are unpinned from the substrate and possibly under low or no tension.
The abrupt change in the configuration of myelin figures from solid tubes to hollow ones was described in a reproducible experiment where the pinned region of the parent stack became unpinned.
Our observations can indicate a relation between the membrane tension of the source material and the diameter of the myelin figures.
American Psychological Association (APA)
Tayebi, Lobat& Mozafari, Masoud& Vashaee, Daryoosh& Parikh, Atul N.. 2012. Structural Configuration of Myelin Figures Using Fluorescence Microscopy. International Journal of Photoenergy،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-490469
Modern Language Association (MLA)
Tayebi, Lobat…[et al.]. Structural Configuration of Myelin Figures Using Fluorescence Microscopy. International Journal of Photoenergy No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-490469
American Medical Association (AMA)
Tayebi, Lobat& Mozafari, Masoud& Vashaee, Daryoosh& Parikh, Atul N.. Structural Configuration of Myelin Figures Using Fluorescence Microscopy. International Journal of Photoenergy. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-490469
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490469