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p53 Family : Role of Protein Isoforms in Human Cancer
Joint Authors
Zaika, Elena
Wei, Jinxiong
Zaika, Alexander
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-09
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
TP53, TP63, and TP73 genes comprise the p53 family.
Each gene produces protein isoforms through multiple mechanisms including extensive alternative mRNA splicing.
Accumulating evidence shows that these isoforms play a critical role in the regulation of many biological processes in normal cells.
Their abnormal expression contributes to tumorigenesis and has a profound effect on tumor response to curative therapy.
This paper is an overview of isoform diversity in the p53 family and its role in cancer.
American Psychological Association (APA)
Wei, Jinxiong& Zaika, Elena& Zaika, Alexander. 2011. p53 Family : Role of Protein Isoforms in Human Cancer. Journal of Nucleic Acids،Vol. 2012, no. 2012, pp.1-19.
https://search.emarefa.net/detail/BIM-490638
Modern Language Association (MLA)
Wei, Jinxiong…[et al.]. p53 Family : Role of Protein Isoforms in Human Cancer. Journal of Nucleic Acids No. 2012 (2012), pp.1-19.
https://search.emarefa.net/detail/BIM-490638
American Medical Association (AMA)
Wei, Jinxiong& Zaika, Elena& Zaika, Alexander. p53 Family : Role of Protein Isoforms in Human Cancer. Journal of Nucleic Acids. 2011. Vol. 2012, no. 2012, pp.1-19.
https://search.emarefa.net/detail/BIM-490638
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490638