![](/images/graphics-bg.png)
In Vitro and In Vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract against Salmonella
Joint Authors
Brice, Obiang-Obounou
Rho, Jung-Rae
Chae, Hee-Sung
Kwon, Dong-Yeul
Kim, Hun-Soo
Oh, You-Chang
Sohn, Dong-Hwan
Lee, Young-Seob
Kim, Min-San
Kang, Ok-Hwa
Choi, Jang-Gi
Park, Hyun
Shin, Dong-Won
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-01-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Punica granatum is commonly used in Korea as a traditional medicine for the treatment of pathogenic bacteria.
In this study, we investigated the in vitro and in vivo antimicrobial activity of P.
granatum peel EtOH extract (PGPE) against 16 strains of Salmonella.
The minimal inhibitory concentrations of PGPE were in the range of 62.5–1000 x03BCg mL-1.
In addition, the in vivo antibacterial activity of the PGPE extract was examined in a S.
typhimurium infection mouse model.
Mice were initially infected with S.
typhimurium and then with PGPE.
The extract was found to have significant effects on mortality and the numbers of viable S.
typhimurium recovered from feces.
Although clinical signs and histological damage were rarely observed in the treated mice, the untreated controls showed signs of lethargy and histological damage in the liver and spleen.
Taken together, the results of this study indicate that PGPE has the potential to provide an effective treatment for salmonellosis.
American Psychological Association (APA)
Choi, Jang-Gi& Kang, Ok-Hwa& Lee, Young-Seob& Chae, Hee-Sung& Oh, You-Chang& Brice, Obiang-Obounou…[et al.]. 2011. In Vitro and In Vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract against Salmonella. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-490828
Modern Language Association (MLA)
Choi, Jang-Gi…[et al.]. In Vitro and In Vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract against Salmonella. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-490828
American Medical Association (AMA)
Choi, Jang-Gi& Kang, Ok-Hwa& Lee, Young-Seob& Chae, Hee-Sung& Oh, You-Chang& Brice, Obiang-Obounou…[et al.]. In Vitro and In Vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract against Salmonella. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-490828
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490828