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Risk Factors for Development of Acute Kidney Injury in Critically Ill Patients : A Systematic Review and Meta-Analysis of Observational Studies
Joint Authors
Plataki, Maria
Casey, Edward T.
Kashiouris, Markos
Gajic, Ognjen
Kor, Daryl J.
Cartin-Ceba, Rodrigo
Source
Critical Care Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-26
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Background.
Acute kidney injury (AKI) is a frequent complication of critically ill patients.
The impact of different risk factors associated with this entity in the ICU setting is unknown.
Objectives.
The purpose of this research was to assess the risk factors associated with the development of AKI in critically ill patients by meta-analyses of observational studies.
Data Extraction.
Two reviewers independently and in duplicate used a standardized form to collect data from published reports.
Authors were contacted for missing data.
The Newcastle-Ottawa scale assessed study quality.
Data Synthesis.
Data from 31 diverse studies that enrolled 504,535 critically ill individuals from a wide variety of ICUs were included.
Separate random-effects meta-analyses demonstrated a significantly increased risk of AKI with older age, diabetes, hypertension, higher baseline creatinine, heart failure, sepsis/systemic inflammatory response syndrome, use of nephrotoxic drugs, higher severity of disease scores, use of vasopressors/inotropes, high risk surgery, emergency surgery, use of intra-aortic balloon pump, and longer time in cardiopulmonary bypass pump.
Conclusion.
The best available evidence suggests an association of AKI with 13 different risk factors in subjects admitted to the ICU.
Predictive models for identification of high risk individuals for developing AKI in all types of ICU are required.
American Psychological Association (APA)
Cartin-Ceba, Rodrigo& Kashiouris, Markos& Plataki, Maria& Kor, Daryl J.& Gajic, Ognjen& Casey, Edward T.. 2012. Risk Factors for Development of Acute Kidney Injury in Critically Ill Patients : A Systematic Review and Meta-Analysis of Observational Studies. Critical Care Research and Practice،Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-490876
Modern Language Association (MLA)
Cartin-Ceba, Rodrigo…[et al.]. Risk Factors for Development of Acute Kidney Injury in Critically Ill Patients : A Systematic Review and Meta-Analysis of Observational Studies. Critical Care Research and Practice No. 2012 (2012), pp.1-15.
https://search.emarefa.net/detail/BIM-490876
American Medical Association (AMA)
Cartin-Ceba, Rodrigo& Kashiouris, Markos& Plataki, Maria& Kor, Daryl J.& Gajic, Ognjen& Casey, Edward T.. Risk Factors for Development of Acute Kidney Injury in Critically Ill Patients : A Systematic Review and Meta-Analysis of Observational Studies. Critical Care Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-490876
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490876