CZEPAD and HPLC-UVPAD Profile of Flavonoids from Maytenus aquifolium and Maytenus ilicifolia “espinheira santa” Leaves Extracts

Abstract EN

This paper describes the application of HPLC and CZE to analyze flavonoids in the leaves of Maytenus ilicifolia and Maytenus aquifolium, which are species widely used in Brazilian folk medicine.

The two species showed different flavonoid profiles, but acidic hydrolysis of the Maytenus extracts confirmed that all these compounds are quercetin or kaempferol derivatives.

A comparison of the CZE and HPLC profiles of Maytenus extracts showed numerous flavonoid peaks using HPLC.

However, the advantages of CZE such as analysis without requiring clean-up and less generation of chemical waste than with HPLC point to the potential of the CZE technique for the quality control (routine analysis) of “espinheira santa” phytopharmaceuticals.