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High-Risk Human Papillomavirus Is Associated with HIV Acquisition among South African Female Sex Workers
Joint Authors
Lissouba, Pascale
Auvert, Bertran
Ramjee, Gita
Zarca, Kevin
Marais, Dianne
Williamson, Anna-Lise
Source
Infectious Diseases in Obstetrics and Gynecology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-24
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
Mounting evidence suggests an association between human papillomavirus (HPV) and HIV acquisition.
This study aimed to explore this association among South African female sex workers (FSWs).
Methods.
We used data from 88 HIV-negative FSWs who participated in a vaginal gel (COL-1492) trial.
Cervicovaginal rinse samples, obtained before HIV-seroconversion, were genotyped into high-risk (HR-) and low-risk (LR-) HPV.
HIV-adjusted hazard ratios (aHRs) and 95% confidence intervals (CI) were estimated using Cox survival analysis.
Results.
HR- and LR-HPV prevalences were 70.5% (95% CI : 60.5–79.2) and 60.2% (95% CI : 49.9–70.0), respectively.
Twenty-five women HIV seroconverted.
Controlling for background characteristics and other sexually transmitted infections, HIV aHR increased by a factor of 1.7 (95% CI : 1.01–2.7, Plinear trend = 0.045) for an increase of one unit of the number of HR-HPV genotypes.
Conclusions.
HIV seroconversion among FSWs is associated with genital HR-HPV infection.
Further investigation is warranted, including testing the possible protective effect of available HPV vaccines on HIV acquisition.
American Psychological Association (APA)
Auvert, Bertran& Marais, Dianne& Lissouba, Pascale& Zarca, Kevin& Ramjee, Gita& Williamson, Anna-Lise. 2011. High-Risk Human Papillomavirus Is Associated with HIV Acquisition among South African Female Sex Workers. Infectious Diseases in Obstetrics and Gynecology،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-490972
Modern Language Association (MLA)
Auvert, Bertran…[et al.]. High-Risk Human Papillomavirus Is Associated with HIV Acquisition among South African Female Sex Workers. Infectious Diseases in Obstetrics and Gynecology No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-490972
American Medical Association (AMA)
Auvert, Bertran& Marais, Dianne& Lissouba, Pascale& Zarca, Kevin& Ramjee, Gita& Williamson, Anna-Lise. High-Risk Human Papillomavirus Is Associated with HIV Acquisition among South African Female Sex Workers. Infectious Diseases in Obstetrics and Gynecology. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-490972
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490972