Synthesis and Bioevaluation of Thieno[2,3-d]pyrimidinone Derivatives as Potential Tumor Cell Growth Inhibitors
Joint Authors
Li, Huangyong
Chen, Changshui
Cao, Xiufang
Xu, Shengzhen
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-07
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A series of novel cycloalkylthieno[2,3-d]pyrimidinone derivatives have been conveniently synthesized via three steps including G-3CR, heterocyclization, and alkylation reactions as a part of our ongoing search for new bioactive molecules.
The newly synthesized compounds were evaluated for their potential tumor cell growth inhibitory activity by standard MTT assay.
The preliminary results show that compound 6b exhibited better inhibitory activities against HepG2, MCF-7, and BCG-823 cell lines compared to the control.
American Psychological Association (APA)
Li, Huangyong& Chen, Changshui& Xu, Shengzhen& Cao, Xiufang. 2013. Synthesis and Bioevaluation of Thieno[2,3-d]pyrimidinone Derivatives as Potential Tumor Cell Growth Inhibitors. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-490980
Modern Language Association (MLA)
Li, Huangyong…[et al.]. Synthesis and Bioevaluation of Thieno[2,3-d]pyrimidinone Derivatives as Potential Tumor Cell Growth Inhibitors. Journal of Chemistry No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-490980
American Medical Association (AMA)
Li, Huangyong& Chen, Changshui& Xu, Shengzhen& Cao, Xiufang. Synthesis and Bioevaluation of Thieno[2,3-d]pyrimidinone Derivatives as Potential Tumor Cell Growth Inhibitors. Journal of Chemistry. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-490980
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490980