The Effect of Safflower Yellow on Spinal Cord Ischemia Reperfusion Injury in Rabbits
Joint Authors
Zhou, Daiwei
Huang, Weihua
Dai, Peng
Ma, Songmei
Liu, Bingbing
Xiao, Xiaoshan
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-07
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Safflower yellow (SY) is the safflower extract and is the one of traditional Chinese medicine.
The aim of the present work was to investigate the effect of SY on spinal cord ischemia reperfusion injury (SCIRI) in rabbits.
The models of spinal cord ischemia reperfusion (SI/R) were constructed, and the degree of the post-ischemic injury was assessed by means of the neurological deficit scores and plasma levels of lipid peroxidation reactioin and neuronal morphologic changes.
SCIRI remarkably affected the functional activities of the hind limbs and activated lipid peroxidation reaction.
SY could attenuate apoptosis and SCIRI by enhancing Bcl-2 expression and inhibiting Bax and caspase-3 activation.
American Psychological Association (APA)
Zhou, Daiwei& Liu, Bingbing& Xiao, Xiaoshan& Dai, Peng& Ma, Songmei& Huang, Weihua. 2013. The Effect of Safflower Yellow on Spinal Cord Ischemia Reperfusion Injury in Rabbits. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-490992
Modern Language Association (MLA)
Zhou, Daiwei…[et al.]. The Effect of Safflower Yellow on Spinal Cord Ischemia Reperfusion Injury in Rabbits. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-490992
American Medical Association (AMA)
Zhou, Daiwei& Liu, Bingbing& Xiao, Xiaoshan& Dai, Peng& Ma, Songmei& Huang, Weihua. The Effect of Safflower Yellow on Spinal Cord Ischemia Reperfusion Injury in Rabbits. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-490992
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-490992