Evaluation of Eye Irritation Potential of Aqueous Leaf Extract of Achyranthes aspera by In Vitro and In Vivo Method
Joint Authors
Rajpal Deshmukh, Gajanan
Venkata Satish Kumar, Chirumamilla
Suresh Reddy, Poojari Venkata
Hema Kumar, Kuntrapakam
Srinivasa Rao, Boddapati
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The present paper is an attempt to investigate the eye irritation potential of aqueous leaf extract of Achyranthes aspera by in vitro, Hen's Egg Chorioallantoic Membrane Test (HET-CAM) and in vivo acute eye irritation test in rabbits.
The irritation score (IS) obtained after treatment of the extract on HET-CAM is 0.07 and that of in rabbits is 0.55, Which does not comes under either category 1 or 2 as per the harmonized integrated classification system.
The aqueous extract of Achyranthes aspera showed no eye irritation properties both in vitro and in vivo methods when compared with negative control whereas positive controls showed eye irritation potential.
American Psychological Association (APA)
Rajpal Deshmukh, Gajanan& Hema Kumar, Kuntrapakam& Suresh Reddy, Poojari Venkata& Srinivasa Rao, Boddapati& Venkata Satish Kumar, Chirumamilla. 2012. Evaluation of Eye Irritation Potential of Aqueous Leaf Extract of Achyranthes aspera by In Vitro and In Vivo Method. ISRN Toxicology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-491100
Modern Language Association (MLA)
Rajpal Deshmukh, Gajanan…[et al.]. Evaluation of Eye Irritation Potential of Aqueous Leaf Extract of Achyranthes aspera by In Vitro and In Vivo Method. ISRN Toxicology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-491100
American Medical Association (AMA)
Rajpal Deshmukh, Gajanan& Hema Kumar, Kuntrapakam& Suresh Reddy, Poojari Venkata& Srinivasa Rao, Boddapati& Venkata Satish Kumar, Chirumamilla. Evaluation of Eye Irritation Potential of Aqueous Leaf Extract of Achyranthes aspera by In Vitro and In Vivo Method. ISRN Toxicology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-491100
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491100
