Synthesis and Analgesic Activity of Novel Derivatives of 1,2-Substituted Benzimidazoles

Joint Authors

Singh, B. K.
Pandeya, Surendra N.
Yadav, Meena K.
Srivastava, Shobhit

Source

Journal of Chemistry

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2012-11-11

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Chemistry

Abstract EN

A series of novel 2-phenylhydrazinomethyl and 2-(2-hydroxyphenyl)-benzimidazole derivatives substituted at the N1-position of benzimidazole nucleus were synthesized as well as screened for analgesic activity.

Some of these compounds showed promising analgesic activity when compared with the standard drug diclofenac sodium.

The incorporation of a phenylhydrazinomethyl nucleus at 2-position of benzimidazole compound gave a biologically active pharmacophore.

American Psychological Association (APA)

Srivastava, Shobhit& Pandeya, Surendra N.& Yadav, Meena K.& Singh, B. K.. 2012. Synthesis and Analgesic Activity of Novel Derivatives of 1,2-Substituted Benzimidazoles. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-491175

Modern Language Association (MLA)

Srivastava, Shobhit…[et al.]. Synthesis and Analgesic Activity of Novel Derivatives of 1,2-Substituted Benzimidazoles. Journal of Chemistry No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-491175

American Medical Association (AMA)

Srivastava, Shobhit& Pandeya, Surendra N.& Yadav, Meena K.& Singh, B. K.. Synthesis and Analgesic Activity of Novel Derivatives of 1,2-Substituted Benzimidazoles. Journal of Chemistry. 2012. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-491175

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-491175