An In Vivo and In Vitro Evaluation of the Mutual Interactions between the Lung and the Large Intestine
Joint Authors
Yan, Xing-Ke
Xu, Yu-Dong
Yang, Yong Qing
Zhang, Guang-Quan
Yin, Lei-Miao
Wang, Yu
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-21
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
One of the most important theories of the traditional Chinese medicine is the exterior-interior relationship between the lung and the large intestine; so far, little direct experimental evidence has been reported to support such relationship.
Here we for the first time investigated the mutual interactions between the lung and the large intestine by examining the relevancies between the pulmonary functions and the rectal resting pressure in the rat models of asthma and constipation.
We also evaluated the effects of the lung homogenate and the large intestine homogenate on the isolated large intestine muscle strip and the isolated tracheal spiral, respectively.
Our results showed that the pulmonary resistance and pulmonary compliance were closely related to the rectal resting pressure in the asthmatic rat model, while the rectal resting pressure was much correlated with the pulmonary resistance in the rat model of constipation.
Moreover, it was shown that the lung homogenate could specifically contract the isolated large intestine muscle strip.
Overall, this study provided new lines of evidence for the theory and highlighted the potential application in the treatment of the corresponding diseases.
American Psychological Association (APA)
Yin, Lei-Miao& Zhang, Guang-Quan& Yan, Xing-Ke& Wang, Yu& Xu, Yu-Dong& Yang, Yong Qing. 2013. An In Vivo and In Vitro Evaluation of the Mutual Interactions between the Lung and the Large Intestine. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-491285
Modern Language Association (MLA)
Yin, Lei-Miao…[et al.]. An In Vivo and In Vitro Evaluation of the Mutual Interactions between the Lung and the Large Intestine. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-491285
American Medical Association (AMA)
Yin, Lei-Miao& Zhang, Guang-Quan& Yan, Xing-Ke& Wang, Yu& Xu, Yu-Dong& Yang, Yong Qing. An In Vivo and In Vitro Evaluation of the Mutual Interactions between the Lung and the Large Intestine. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-491285
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491285