Fasting Blood Glucose and Lipid Profile Alterations following Twelve-Month Androgen Deprivation Therapy in Men with Prostate Cancer
Joint Authors
Köse, Osman
Adsan, Öztuğ
Kumsar, Şükrü
Sağlam, Hasan S.
Budak, Salih
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-17
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Purpose.
In this retrospective study, we aimed to investigate the effects of androgen deprivation therapy (ADT) on blood glucose and blood cholesterol levels over a 12-month period.
Materials and Methods.
Between January 2010 and June 2012, the data of 44 patients with prostate cancer who were receiving ADT were collected from a hospital database.
Patients with additional malignancy or diabetes and those who had been prescribed and were currently taking cholesterol-lowering medication were excluded from the study.
Data (including fasting blood glucose levels and a cholesterol profile) were collected and analysed statistically.
A P value <0.05 was considered statistically significant.
Results.
Twelve months after the initiation of ADT, fasting blood glucose (FBG), total cholesterol (TC), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and triglyceride (TG) levels changed.
FBG, TC, LDL cholesterol, and TG increased significantly (P=0.009, 0.000, 0.000, and 0.000, resp.), while HDL cholesterol decreased (P=0.000).
Conclusion.
ADT may increase FBG, TC, LDL cholesterol, and TG but decrease HDL cholesterol by the end of a year of treatment.
Therefore, close followup may be needed as a consequence of one-year ADT regarding metabolic alterations.
American Psychological Association (APA)
Sağlam, Hasan S.& Köse, Osman& Kumsar, Şükrü& Budak, Salih& Adsan, Öztuğ. 2012. Fasting Blood Glucose and Lipid Profile Alterations following Twelve-Month Androgen Deprivation Therapy in Men with Prostate Cancer. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-491352
Modern Language Association (MLA)
Sağlam, Hasan S.…[et al.]. Fasting Blood Glucose and Lipid Profile Alterations following Twelve-Month Androgen Deprivation Therapy in Men with Prostate Cancer. The Scientific World Journal No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-491352
American Medical Association (AMA)
Sağlam, Hasan S.& Köse, Osman& Kumsar, Şükrü& Budak, Salih& Adsan, Öztuğ. Fasting Blood Glucose and Lipid Profile Alterations following Twelve-Month Androgen Deprivation Therapy in Men with Prostate Cancer. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-491352
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491352