F18-FLT PETCT in Patients with Gastric Carcinoma
Joint Authors
Staniuk, Tomasz
Zegarski, Wojciech
Małkowski, Bogdan
Śrutek, Ewa
Studniarek, Michał
Gorycki, Tomasz
Source
Gastroenterology Research and Practice
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The aim of the study was to evaluate the usefulness of 18F-FLT PET/CT in the detection and differentiation of gastric cancers (GC).
104 consecutive patients (57 cases of adenocarcinoma tubulare (G2 and G3), 17 cases of mucinous adenocarcinoma, 6 cases of undifferentiated carcinoma, 14 cases of adenocarcinoma partim mucocellulare, and 10 cases of end stage gastric cancer) with newly diagnosed advanced gastric cancer were examined with FLT PET/CT.
For quantitative and comparative analyses, the maximal standardized uptake value (SUVmax) was calculated for both the tumors and noninvaded gastric wall.
Results.
There were found, in the group of adenocarcinoma tubulare, SUVmax 1.5–23.1 (7.46±4.57), in mucinous adenocarcinoma, SUVmax 2.3–10.3 (5.5±2.4), in undifferentiated carcinoma, SUVmax 3.1–13.6 (7.28±3.25), in adenocarcinoma partim mucocellulare, SUVmax 2–25.3 (7.7±6.99), and, in normal gastric wall, SUVmax 1.01–2.55 (1.84±0.35).
For the level of 2.6 cut-off value between the normal wall and neoplasm FLT uptake from ROC analysis, all but five gastric cancers showed higher accumulation of FLT than noninfiltrated mucosa.
Conclusion.
Gastric cancer presents higher accumulation of 18F-FLT than normal, distended gastric mucosa.
Significantly higher accumulation was shown in cancers better differentiated and with higher cellular density.
American Psychological Association (APA)
Małkowski, Bogdan& Staniuk, Tomasz& Śrutek, Ewa& Gorycki, Tomasz& Zegarski, Wojciech& Studniarek, Michał. 2013. F18-FLT PETCT in Patients with Gastric Carcinoma. Gastroenterology Research and Practice،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-491359
Modern Language Association (MLA)
Małkowski, Bogdan…[et al.]. F18-FLT PETCT in Patients with Gastric Carcinoma. Gastroenterology Research and Practice No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-491359
American Medical Association (AMA)
Małkowski, Bogdan& Staniuk, Tomasz& Śrutek, Ewa& Gorycki, Tomasz& Zegarski, Wojciech& Studniarek, Michał. F18-FLT PETCT in Patients with Gastric Carcinoma. Gastroenterology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-491359
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491359