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Glycerol Carbonate : A Novel Biosolvent with Strong Ionizing and Dissociating Powers
Joint Authors
He, Biyan
Ou, Guangnan
Lei, Jianhui
Li, Xuejing
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
The activity of biocatalysts in nonaqueous solvents is related to the interaction of organic solvents with cells or enzymes.
The behavior of proteins is strongly dependent on the protonation state of their ionizable groups, which ionization constants are greatly affected by the solvent.
Due to the weak ionizing and dissociating powers of common organic solvents, the charge of the protein will change significantly when the protein is transferred from water to common organic solvents, resulting in protein denaturation.
In this work, glycerol carbonate (GC) was synthesized, which ionizing and dissociating abilities were very close to those of water.
Transesterification activities of Candida antarctica lipase B (CALB) in GC were comparable to those in water and remained constant during 4-week storage.
Bacillus subtilis and Saccharomyecs cerevisiae were cultured in liquid media containing GC with test tubes.
In the medium containing low GC concentration, Bacillus subtilis and Saccharomyecs cerevisiae grew well as in a medium containing no organic solvent, but, in the medium containing high GC concentration, the growth of Bacillus subtilis and Saccharomyecs cerevisiae was suppressed.
The results suggested that GC is a potential biosolvent, which has great significance to biocatalysis in nonaqueous solvents.
American Psychological Association (APA)
Ou, Guangnan& He, Biyan& Li, Xuejing& Lei, Jianhui. 2012. Glycerol Carbonate : A Novel Biosolvent with Strong Ionizing and Dissociating Powers. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-491417
Modern Language Association (MLA)
Ou, Guangnan…[et al.]. Glycerol Carbonate : A Novel Biosolvent with Strong Ionizing and Dissociating Powers. The Scientific World Journal No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-491417
American Medical Association (AMA)
Ou, Guangnan& He, Biyan& Li, Xuejing& Lei, Jianhui. Glycerol Carbonate : A Novel Biosolvent with Strong Ionizing and Dissociating Powers. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-491417
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491417