![](/images/graphics-bg.png)
The Immune Response : Targets for the Treatment of Severe Sepsis
Joint Authors
Bernard, Gordon R.
Bernard, Aline M.
Source
International Journal of Inflammation
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The clinical process of severe sepsis is characterized by extreme inflammation interlinked with potent stimulation of the coagulation cascade often followed by a state of relative immune paralysis.
In this paper, we will review many of the potential therapies directed at various steps along the inflammatory cascade from modulation of inflammatory mediators eliciting the immune response, alteration of the host's immune response in both a stimulatory and depressive manner, and taming the overexuberant coagulation response triggered by the fierce coagulation-inflammation cycle.
Finally, we will discuss further opportunities for research to improve our ability to design effective therapies.
American Psychological Association (APA)
Bernard, Aline M.& Bernard, Gordon R.. 2012. The Immune Response : Targets for the Treatment of Severe Sepsis. International Journal of Inflammation،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-491459
Modern Language Association (MLA)
Bernard, Aline M.& Bernard, Gordon R.. The Immune Response : Targets for the Treatment of Severe Sepsis. International Journal of Inflammation No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-491459
American Medical Association (AMA)
Bernard, Aline M.& Bernard, Gordon R.. The Immune Response : Targets for the Treatment of Severe Sepsis. International Journal of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-491459
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491459