Synthesis of Isatin Derivative on the Short Multiwalled Carbon Nanotubes and Their Effect on the MKN-45 and SW742 Cancer Cells
Joint Authors
Chitgar, Farshid
Tahermansouri, Hasan
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-06
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The carboxylated short multiwalled carbon nanotubes (Sh-MWCNT-COOH) were first modified by isatin derivative to form Sh-MWCNT-Amide and then by hydrazine to produce Sh-MWCNT-Spiro.
All products were characterized by the Fourier transform infrared spectroscopy, Raman spectroscopy, scanning electron microscope, elemental analysis, thermogravimetric analysis, derivative thermogravimetric, solubility test, and cellular investigations.
This functionalization has been chosen due to active sites of OH and carbonyl groups in Sh-MWCNT-Amide which might be used as functional materials in the future.
Toxicity of these samples was evaluated with human gastric and colon cancer cells, and killed cell numbers were measured by reduction of living cells with 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium bromide.
Cellular results showed high toxicity of Sh-MWCNT-Amide in all samples investigated.
American Psychological Association (APA)
Tahermansouri, Hasan& Chitgar, Farshid. 2013. Synthesis of Isatin Derivative on the Short Multiwalled Carbon Nanotubes and Their Effect on the MKN-45 and SW742 Cancer Cells. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-491475
Modern Language Association (MLA)
Tahermansouri, Hasan& Chitgar, Farshid. Synthesis of Isatin Derivative on the Short Multiwalled Carbon Nanotubes and Their Effect on the MKN-45 and SW742 Cancer Cells. Journal of Chemistry No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-491475
American Medical Association (AMA)
Tahermansouri, Hasan& Chitgar, Farshid. Synthesis of Isatin Derivative on the Short Multiwalled Carbon Nanotubes and Their Effect on the MKN-45 and SW742 Cancer Cells. Journal of Chemistry. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-491475
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491475