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Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio : Novel Markers for Diagnosis and Prognosis in Patients with Idiopathic Sudden Sensorineural Hearing Loss
Joint Authors
Seo, Young Joon
Choi, Jae Young
Moon, In Seok
Jeong, Jun hui
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-07
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
We aim to provide useful evidence about the association of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with idiopathic sudden sensorineural hearing loss (ISSNHL) and its possibility of emerging as a cheap, reliable, and independent prognostic marker of ISSNHL.
Methods.
348 patients diagnosed with ISSNHL were included in our retrospective data analysis.
Blood samples and the hearing assessments of the patients were carried out.
Then, the patients were divided into 2 groups as “recovered” and “unrecovered” according to their response to the treatment.
Results.
Both mean NLR and PLR values of the ISSNHL patients were significantly higher than the control group (both P<0.001).
The NLR value was 5.98±4.22 in the unrecovered group and 3.50±3.38 in the recovered group (P<0.001).
After adjustment in a binary logistic regression model, only NLR value was associated with the recovery of ISSNHL (P=0.001).
Discussion.
We demonstrated for the first time that NLR and PLR values were significantly high in ISSNHL patients.
Also the NLR level might be taken into account as a novel potential marker to predict the patients’ prognosis in terms of recovery.
American Psychological Association (APA)
Seo, Young Joon& Jeong, Jun hui& Choi, Jae Young& Moon, In Seok. 2014. Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio : Novel Markers for Diagnosis and Prognosis in Patients with Idiopathic Sudden Sensorineural Hearing Loss. Disease Markers،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-491757
Modern Language Association (MLA)
Seo, Young Joon…[et al.]. Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio : Novel Markers for Diagnosis and Prognosis in Patients with Idiopathic Sudden Sensorineural Hearing Loss. Disease Markers No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-491757
American Medical Association (AMA)
Seo, Young Joon& Jeong, Jun hui& Choi, Jae Young& Moon, In Seok. Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio : Novel Markers for Diagnosis and Prognosis in Patients with Idiopathic Sudden Sensorineural Hearing Loss. Disease Markers. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-491757
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491757