Alterations of the Erythrocyte Membrane during Sepsis
Joint Authors
Djebara, Sarah
Piagnerelli, Michael
Serroukh, Yasmina
Biston, Patrick
Lelubre, Christophe
Zouaoui Boudjeltia, Karim
Source
Critical Care Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Erythrocytes have been long considered as “dead” cells with transport of oxygen (O2) as their only function.
However, the ability of red blood cells (RBCs) to modulate the microcirculation is now recognized as an important additional function.
This capacity is regulated by a key element in the rheologic process: the RBC membrane.
This membrane is a complex unit with multiple interactions between the extracellular and intracellular compartments: blood stream, endothelium, and other blood cells on the one hand, and the intracytoplasmic compartment with possible rapid adaptation of erythrocyte metabolism on the other.
In this paper, we review the alterations in the erythrocyte membrane observed in critically ill patients and the influence of these alterations on the microcirculatory abnormalities observed in such patients.
An understanding of the mechanisms of RBC rheologic alterations in sepsis and their effects on blood flow and on oxygen transport may be important to help reduce morbidity and mortality from severe sepsis.
American Psychological Association (APA)
Serroukh, Yasmina& Djebara, Sarah& Lelubre, Christophe& Zouaoui Boudjeltia, Karim& Biston, Patrick& Piagnerelli, Michael. 2012. Alterations of the Erythrocyte Membrane during Sepsis. Critical Care Research and Practice،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-491778
Modern Language Association (MLA)
Serroukh, Yasmina…[et al.]. Alterations of the Erythrocyte Membrane during Sepsis. Critical Care Research and Practice No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-491778
American Medical Association (AMA)
Serroukh, Yasmina& Djebara, Sarah& Lelubre, Christophe& Zouaoui Boudjeltia, Karim& Biston, Patrick& Piagnerelli, Michael. Alterations of the Erythrocyte Membrane during Sepsis. Critical Care Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-491778
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491778