Redox Regulation of Cysteine-Dependent Enzymes in Neurodegeneration
Joint Authors
Guttmann, Rodney P.
Powell, Tamara J.
Source
International Journal of Cell Biology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-05
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Evidence of increased oxidative stress has been found in various neurodegenerative diseases and conditions.
While it is unclear whether oxidative stress is a cause or effect, protein, lipid, and DNA have all been found to be susceptible to oxidant-induced modifications that alter their function.
Results of clinical trials based on the oxidative-stress theory have been mixed, though data continues to indicate that prevention of high levels of oxidative stress is beneficial for health and increases longevity.
Due to the highly reactive nature of the sulfhydryl group, the focus of this paper is on the impact of oxidative stress on cysteine-dependent enzymes and how oxidative stress may contribute to neurological dysfunction through this selected group of proteins.
American Psychological Association (APA)
Guttmann, Rodney P.& Powell, Tamara J.. 2012. Redox Regulation of Cysteine-Dependent Enzymes in Neurodegeneration. International Journal of Cell Biology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-491799
Modern Language Association (MLA)
Guttmann, Rodney P.& Powell, Tamara J.. Redox Regulation of Cysteine-Dependent Enzymes in Neurodegeneration. International Journal of Cell Biology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-491799
American Medical Association (AMA)
Guttmann, Rodney P.& Powell, Tamara J.. Redox Regulation of Cysteine-Dependent Enzymes in Neurodegeneration. International Journal of Cell Biology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-491799
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491799