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SOD-Mimic Cu(II) Dimeric Complexes Involving Kinetin and Its Derivative : Preparation and Characterization
Joint Authors
Herchel, Radovan
Trávníček, Zdeněk
Novotná, Radka
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Two SOD-mimic active dimeric Cu(II) chlorido complexes of the compositions [Cu2(μ-HL1)4Cl2]Cl2 (1) and [Cu2(μ-HL2)2(μ-Cl)2(HL2)2Cl2] · 4H2O (2) involving the cosmetologically relevant cytokinin kinetin (N6-furfuryladenine, HL1) and its derivative N6-(5-methylfurfuryl)adenine (HL2) have been synthesized and characterized by elemental analysis, infrared, and electronic spectroscopy, ESI+ mass spectrometry, conductivity and temperature dependence of magnetic susceptibility measurements, and thermogravimetric (TG) and differential thermal (DTA) analyses.
The results of these methods, particularly the temperature dependence of magnetic susceptibility, showed the complexes to be dimeric with a strong antiferromagnetic exchange (J = −290 cm−1 for complex 1 and J = −160 cm−1 for 2).
The complexes have been identified as auspicious SOD-mimics, as their antiradical activity evaluated by the in vitro SOD-mimic assay resulted in the IC50 values equal to 8.13 μM (1) and 0.71 μM (2).
American Psychological Association (APA)
Novotná, Radka& Trávníček, Zdeněk& Herchel, Radovan. 2012. SOD-Mimic Cu(II) Dimeric Complexes Involving Kinetin and Its Derivative : Preparation and Characterization. Bioinorganic Chemistry and Applications،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-491919
Modern Language Association (MLA)
Novotná, Radka…[et al.]. SOD-Mimic Cu(II) Dimeric Complexes Involving Kinetin and Its Derivative : Preparation and Characterization. Bioinorganic Chemistry and Applications No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-491919
American Medical Association (AMA)
Novotná, Radka& Trávníček, Zdeněk& Herchel, Radovan. SOD-Mimic Cu(II) Dimeric Complexes Involving Kinetin and Its Derivative : Preparation and Characterization. Bioinorganic Chemistry and Applications. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-491919
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491919