![](/images/graphics-bg.png)
Patterns in the Parathyroid Response to Sodium Bicarbonate Infusion Test in Healthy Volunteers
Joint Authors
Anastasiou, Olympia E.
Papavramidis, Spiros
Pliakos, Ioannis
Polyzonis, Mike
Papavramidis, Theodossis S.
Michalopoulos, Nick
Triantafyllopoulou, Konstantina
Kokaraki, Georgia
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-08
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
The sodium bicarbonate infusion test evaluates the function of the parathyroid glands.
The present study aims to evaluate the range of parathyroid response in healthy individuals and the potential influence of various factors.
Methods.
Fifty healthy volunteers were subjected to the test.
Levels of vitamin D, calcium, albumin, and PTH were measured before infusion.
PTH was measured at 3, 5, 10, 30, and 60 minutes after infusion.
Results.
A curve describing the response of parathyroids to the test was drawn.
Twenty percent of the subjects had blunted PTH response.
No significant difference was observed between normal and blunted responders concerning age, BMI, baseline PTH, or calcium levels.
Nonetheless, there was a significant difference in vitamin D levels (P=0.024).
Interpretation.
The test is easy to perform and may be used for everyday screening.
It has to be clarified whether our observations are, at least partly, produced due to the presence of individuals with a constitutively blunted response or if low levels of vitamin D decrease the ability of the parathyroids to respond.
Whichever the case, PTH response of normal individuals to sodium bicarbonate infusion test is more varied than previously thought and vitamin D levels influence it.
American Psychological Association (APA)
Papavramidis, Theodossis S.& Anastasiou, Olympia E.& Pliakos, Ioannis& Michalopoulos, Nick& Polyzonis, Mike& Triantafyllopoulou, Konstantina…[et al.]. 2014. Patterns in the Parathyroid Response to Sodium Bicarbonate Infusion Test in Healthy Volunteers. BioMed Research International،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-491923
Modern Language Association (MLA)
Papavramidis, Theodossis S.…[et al.]. Patterns in the Parathyroid Response to Sodium Bicarbonate Infusion Test in Healthy Volunteers. BioMed Research International No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-491923
American Medical Association (AMA)
Papavramidis, Theodossis S.& Anastasiou, Olympia E.& Pliakos, Ioannis& Michalopoulos, Nick& Polyzonis, Mike& Triantafyllopoulou, Konstantina…[et al.]. Patterns in the Parathyroid Response to Sodium Bicarbonate Infusion Test in Healthy Volunteers. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-491923
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491923