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Mixed Acinar-Neuroendocrine Carcinoma of the Pancreas with Neuroendocrine Predominance
Joint Authors
Saif, Muhammad Wasif
Ogbonna, Onyekachi Henry
Garcon, Marie Carmel
Syrigos, Kostas N.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-17
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Background.
Pancreatic tumors are rare and could arise from either the exocrine (ductal and acinar cells) or the endocrine (neuroendocrine cells) components of the pancreas.
In some instances, the occurrence of pancreatic tumors comprising both acinar cells and neuroendocrine cells, with neuroendocrine cells making up more than 30% of the tumor, has been identified.
This unique entity has been referred to as mixed acinar-neuroendocrine carcinoma (MANEC).
Only about 20 such cases have been reported in the literature.
Case Report.
We report an interesting case of MANEC with neuroendocrine cell predominance in a woman presenting with epigastric pain secondary to a pancreatic mass with acinar and endocrine differentiation.
She underwent surgical resection of the tumor and was offered adjuvant treatment chemotherapy with carboplatin, etoposide, and radiotherapy for positive tumor resection margins.
Conclusions.
Given the paucity of the cases of MANEC, continuous reporting of these cases when identified should be encouraged to aid oncologists in understanding the disease and help establish standardized management.
American Psychological Association (APA)
Ogbonna, Onyekachi Henry& Garcon, Marie Carmel& Syrigos, Kostas N.& Saif, Muhammad Wasif. 2013. Mixed Acinar-Neuroendocrine Carcinoma of the Pancreas with Neuroendocrine Predominance. Case Reports in Medicine،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-491980
Modern Language Association (MLA)
Ogbonna, Onyekachi Henry…[et al.]. Mixed Acinar-Neuroendocrine Carcinoma of the Pancreas with Neuroendocrine Predominance. Case Reports in Medicine No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-491980
American Medical Association (AMA)
Ogbonna, Onyekachi Henry& Garcon, Marie Carmel& Syrigos, Kostas N.& Saif, Muhammad Wasif. Mixed Acinar-Neuroendocrine Carcinoma of the Pancreas with Neuroendocrine Predominance. Case Reports in Medicine. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-491980
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491980