Synthesis Characterization and Biological Activity Study of New Schiff and Mannich Bases and Some Metal Complexes Derived from Isatin and Dithiooxamide
Joint Authors
Abdulghani, Ahlam Jameel
Abbas, Nada M.
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-15
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Two new Schiff and Mannich bases, namely, 1-Morpholinomethyl-3(1′ -N-dithiooxamide)iminoisatin (LIH) and 1-diphenylaminomethyl-3-1′-N-dithiooxamide)iminoisatin (LIIH), were prepared from condensation reaction of new Schiff base 3-(1′-N-dithiooxamide)iminoisatin (SBH) with morpholine or diphenylamine respectively in presence of formaldehyde .
The structures were characterized by IR, 1HNMR, mass spectrometry, and CHN analyses.
Metal complexes of the two ligands were synthesized, and their structures were characterized by elemental analyses, atomic absorption, IR and UV-visible spectra, molar conductivity, and magnetic moment determination.
All complexes showed octahedral geometries except palladium complexes which were square planar.
The biological activity of the prepared compounds and some selected metal complexes was tested against three types of bacteria and against cell line of human epidermoid larynx carcinoma (Hep-2).
American Psychological Association (APA)
Abdulghani, Ahlam Jameel& Abbas, Nada M.. 2011. Synthesis Characterization and Biological Activity Study of New Schiff and Mannich Bases and Some Metal Complexes Derived from Isatin and Dithiooxamide. Bioinorganic Chemistry and Applications،Vol. 2011, no. 2011, pp.1-15.
https://search.emarefa.net/detail/BIM-492086
Modern Language Association (MLA)
Abdulghani, Ahlam Jameel& Abbas, Nada M.. Synthesis Characterization and Biological Activity Study of New Schiff and Mannich Bases and Some Metal Complexes Derived from Isatin and Dithiooxamide. Bioinorganic Chemistry and Applications No. 2011 (2011), pp.1-15.
https://search.emarefa.net/detail/BIM-492086
American Medical Association (AMA)
Abdulghani, Ahlam Jameel& Abbas, Nada M.. Synthesis Characterization and Biological Activity Study of New Schiff and Mannich Bases and Some Metal Complexes Derived from Isatin and Dithiooxamide. Bioinorganic Chemistry and Applications. 2011. Vol. 2011, no. 2011, pp.1-15.
https://search.emarefa.net/detail/BIM-492086
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492086