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The Inflammatory Response to Miniaturised Extracorporeal Circulation : A Review of the Literature
Joint Authors
Vohra, Hunaid A.
Ohri, Sunil K.
Whistance, Robert
Modi, Amit
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-01-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Conventional cardiopulmonary bypass can trigger a systemic inflammatory response syndrome similar to sepsis.
Aetiological factors include surgical trauma, reperfusion injury, and, most importantly, contact of the blood with the synthetic surfaces of the heart-lung machine.
Recently, a new cardiopulmonary bypass system, mini-extracorporeal circulation (MECC), has been developed and has shown promising early results in terms of reducing this inflammatory response.
It has no venous reservoir, a reduced priming volume, and less blood-synthetic interface.
This review focuses on the inflammatory and clinical outcomes of using MECC and compares these to conventional cardio-pulmonary bypass (CCPB).
MECC has been shown to reduce postoperative cytokines levels and other markers of inflammation.
In addition, MECC reduces organ damage, postoperative complications and the need for blood transfusion.
MECC is a safe and viable perfusion option and in certain circumstances it is superior to CCPB.
American Psychological Association (APA)
Vohra, Hunaid A.& Whistance, Robert& Modi, Amit& Ohri, Sunil K.. 2010. The Inflammatory Response to Miniaturised Extracorporeal Circulation : A Review of the Literature. Mediators of Inflammation،Vol. 2009, no. 2009, pp.1-7.
https://search.emarefa.net/detail/BIM-492147
Modern Language Association (MLA)
Vohra, Hunaid A.…[et al.]. The Inflammatory Response to Miniaturised Extracorporeal Circulation : A Review of the Literature. Mediators of Inflammation No. 2009 (2009), pp.1-7.
https://search.emarefa.net/detail/BIM-492147
American Medical Association (AMA)
Vohra, Hunaid A.& Whistance, Robert& Modi, Amit& Ohri, Sunil K.. The Inflammatory Response to Miniaturised Extracorporeal Circulation : A Review of the Literature. Mediators of Inflammation. 2010. Vol. 2009, no. 2009, pp.1-7.
https://search.emarefa.net/detail/BIM-492147
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492147