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HOX Gene Aberrant Expression in Skin Melanoma : A Review
Joint Authors
Piérard, Gérald E.
Piérard-Franchimont, Claudine
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-02
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The homeobox family and its subset of HOX gene products represent a family of transcription factors directing DNA-protein and protein-protein interactions.
In the embryo, they are central regulators in cell differentiation during morphogenesis.
A series of genes of the four HOX gene clusters A, B, C, and D were reported to show aberrant expressions in oncogenesis, particularly in cutaneous malignant melanoma (CMM).
They are involved in cell proliferation and progression in the CMM metastatic path.
We present relevant peer-reviewed literature findings about the aberrant expression of HOX genes in CMM.
The number of CMM cell nuclei exhibiting aberrant HOX protein expression appears correlated with tumour progression.
American Psychological Association (APA)
Piérard, Gérald E.& Piérard-Franchimont, Claudine. 2012. HOX Gene Aberrant Expression in Skin Melanoma : A Review. Journal of Skin Cancer،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-492159
Modern Language Association (MLA)
Piérard, Gérald E.& Piérard-Franchimont, Claudine. HOX Gene Aberrant Expression in Skin Melanoma : A Review. Journal of Skin Cancer No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-492159
American Medical Association (AMA)
Piérard, Gérald E.& Piérard-Franchimont, Claudine. HOX Gene Aberrant Expression in Skin Melanoma : A Review. Journal of Skin Cancer. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-492159
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492159