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Safety and Efficacy of Tree Pollen Specific Immunotherapy on the Ultrarush Administration Schedule Method Using Purethal Trees
Joint Authors
Kolodziejczyk, Krzysztof
Jarzab, Jerzy
Bozek, Andrzej
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-24
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Specific immunotherapy (SIT) with an ultrarush administration schedule with Purethal for tree pollen allergens has been evaluated to assess its efficacy and safety.
Methods.
The study group consisted of 22 patients with symptoms of allergic rhinitis and confirmed allergy to tree pollens.
Patients were randomized and given an administration schedule of either ultrarush therapy or conventional preseasonal SIT.
Treatment was performed during three consecutive years.
Results.
After three years of treatment, a similar reduction in nasal symptoms was observed; according to the visual analog scale, there was a decrease from 3.991 ± 0.804 points to 1.634 ± 0.540 in the ultrarush group and from 3.845 ± 0.265 to 1.501 ± 0.418 in the group desensitized using the conventional method (P>0.05).
There was also a comparable reduction in the use of relief drugs during pollen season and an increase in the serum concentration of IgG4 to tree pollens.
No significant differences in the safety profile were observed.
Conclusion.
An administration schedule of ultrarush SIT with Purethal Trees is a safe treatment in preliminary observations.
This therapy is comparable with conventional administration of SIT in the field of efficacy and safety.
American Psychological Association (APA)
Bozek, Andrzej& Kolodziejczyk, Krzysztof& Jarzab, Jerzy. 2014. Safety and Efficacy of Tree Pollen Specific Immunotherapy on the Ultrarush Administration Schedule Method Using Purethal Trees. BioMed Research International،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-492197
Modern Language Association (MLA)
Bozek, Andrzej…[et al.]. Safety and Efficacy of Tree Pollen Specific Immunotherapy on the Ultrarush Administration Schedule Method Using Purethal Trees. BioMed Research International No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-492197
American Medical Association (AMA)
Bozek, Andrzej& Kolodziejczyk, Krzysztof& Jarzab, Jerzy. Safety and Efficacy of Tree Pollen Specific Immunotherapy on the Ultrarush Administration Schedule Method Using Purethal Trees. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-492197
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492197