Relapsed Mantle Cell Lymphoma Presenting as “Sister Mary Joseph Nodule”

Abstract EN

The finding of umbilical metastasis has historically been called a “Sister Mary Joseph Nodule”.

A few case reports of lymphoma presenting in this manner have been documented.

We report a case of relapsed mantle cell lymphoma (MCL) presenting as a Sister Mary Joseph's nodule.

Although the few reports of lymphoma exhibiting umbilical metastasis suggest that patients may still expect a reasonable response to chemotherapy, this patient experienced multiple relapses, despite aggressive chemotherapy regimens.

This clinical course is characteristic of the mantle cell form of non-hodgkin's lymphoma and illustrates a need to seek out more effective therapies.