![](/images/graphics-bg.png)
Treatment-Based Strategy for the Management of Post-Kala-Azar Dermal Leishmaniasis Patients in the Sudan
Joint Authors
Adam, A. O. A.
Elfaki, Mona Elfaki Eltahir
Abuzaid, A. A.
Khalil, Eltahir Awad Gasim
Elamin, M. Y.
El Hassan, Ahmed Mohamed
Younis, B. M.
Dafalla, M. M. M.
Musa, Ahmed Mudawi
Mohamed, H. A. A.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-15
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Post-kala-azar dermal leishmaniasis (PKDL) is a dermatosis that affects more than 50% of successfully treated visceral leishmaniasis (VL) patients in Sudan.
PKDL is considered an important reservoir for the parasite and its treatment may help in the control of VL.
Currently, treatment is mainly with sodium stibogluconate (SSG), an expensive and fairly toxic drug and without universally in treatment protocols used.
A literature review, a consensus of a panel of experts, and unpublished data formed the basis for the development of guidelines for the treatment of PKDL in the Sudan.
Six treatment modalities were evaluated.
Experts were asked to justify their choices based on their experience regarding of drug safety, efficacy, availability, and cost.
The consensus was defined by assigning a categorical rank (first line, second line, third line) to each option.
Regarding the use of AmBisome the presence of the drug in the skin was confirmed in smears from PKDL lesions.
Recommendations: AmBisome at 2.5 mg/kg/day/20 days or SSG at 20 mg/kg/day/40 days plus four/weekly intradermal injection of alum-precipitated autoclave L.
major vaccine are suggested as first- and second-treatment options for PKDL in the Sudan, respectively.
SSG at 20 mg/Kg/day/60 or more days can be used if other options are not available.
American Psychological Association (APA)
Musa, Ahmed Mudawi& Khalil, Eltahir Awad Gasim& Younis, B. M.& Elfaki, Mona Elfaki Eltahir& Elamin, M. Y.& Adam, A. O. A.…[et al.]. 2013. Treatment-Based Strategy for the Management of Post-Kala-Azar Dermal Leishmaniasis Patients in the Sudan. Journal of Tropical Medicine،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-492250
Modern Language Association (MLA)
Musa, Ahmed Mudawi…[et al.]. Treatment-Based Strategy for the Management of Post-Kala-Azar Dermal Leishmaniasis Patients in the Sudan. Journal of Tropical Medicine No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-492250
American Medical Association (AMA)
Musa, Ahmed Mudawi& Khalil, Eltahir Awad Gasim& Younis, B. M.& Elfaki, Mona Elfaki Eltahir& Elamin, M. Y.& Adam, A. O. A.…[et al.]. Treatment-Based Strategy for the Management of Post-Kala-Azar Dermal Leishmaniasis Patients in the Sudan. Journal of Tropical Medicine. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-492250
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492250