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Evaluation of the Wound Healing Potential of Resina Draconis (Dracaena cochinchinensis) in Animal Models
Joint Authors
Gu, Yan
Liu, Huihui
Xiao, Dan
Zheng, Xiao
Lin, Shaohui
Guo, Shanyu
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-16
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Resina Draconis (RD) is a type of dragon's blood resin obtained from Dracaena cochinchinensis (Lour.) S.C.
Chen (Yunnan, China).
It has been used as a medicine since ancient times by many cultures.
The ethanolic extract of Resina Draconis (RDEE) was evaluated for its wound-healing activity using excision and incision wound models in rats.
Group I, the control group, was treated with ointment base.
Group II, which served as a reference standard, was treated with moist exposed burn ointment (MEBO).
Group III was treated with RDEE.
The parameters observed were percentage of wound contraction, epithelialization period, tensile strength, histopathological studies, microvessel density (MVD), and the expression of vascular endothelial growth factor (VEGF) and transforming growth factor-β1 (TGF-β1).
The group treated with RDEE showed significantly better wound contraction and better skin-breaking strength as compared with the control group.
The results of histopathological examination, MVD, and the expression levels of growth factors supported the outcome of the wound models as well.
The present study provided a scientific rationale for the traditional use of RD in the management of wounds.
American Psychological Association (APA)
Liu, Huihui& Lin, Shaohui& Xiao, Dan& Zheng, Xiao& Gu, Yan& Guo, Shanyu. 2013. Evaluation of the Wound Healing Potential of Resina Draconis (Dracaena cochinchinensis) in Animal Models. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-492400
Modern Language Association (MLA)
Liu, Huihui…[et al.]. Evaluation of the Wound Healing Potential of Resina Draconis (Dracaena cochinchinensis) in Animal Models. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-492400
American Medical Association (AMA)
Liu, Huihui& Lin, Shaohui& Xiao, Dan& Zheng, Xiao& Gu, Yan& Guo, Shanyu. Evaluation of the Wound Healing Potential of Resina Draconis (Dracaena cochinchinensis) in Animal Models. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-492400
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492400