The Effect of Ingested Macronutrients on Postprandial Ghrelin Response : A Critical Review of Existing Literature Data
Joint Authors
Koliaki, Chrysi
Tentolouris, Nicholas
Katsilambros, Nicholas L.
Kokkinos, Alexander
Source
International Journal of Peptides
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-02-02
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Ghrelin is a powerful orexigenic gut hormone with growth hormone releasing activity.
It plays a pivotal role for long-term energy balance and short-term food intake.
It is also recognized as a potent signal for meal initiation.
Ghrelin levels rise sharply before feeding onset, and are strongly suppressed by food ingestion.
Postprandial ghrelin response is totally macronutrient specific in normal weight subjects, but is rather independent of macronutrient composition in obese.
In rodents and lean individuals, isoenergetic meals of different macronutrient content suppress ghrelin to a variable extent.
Carbohydrate appears to be the most effective macronutrient for ghrelin suppression, because of its rapid absorption and insulin-secreting effect.
Protein induces prolonged ghrelin suppression and is considered to be the most satiating macronutrient.
Fat, on the other hand, exhibits rather weak and insufficient ghrelin-suppressing capacity.
The principal mediators involved in meal-induced ghrelin regulation are glucose, insulin, gastrointestinal hormones released in the postabsorptive phase, vagal activity, gastric emptying rate, and postprandial alterations in intestinal osmolarity.
American Psychological Association (APA)
Koliaki, Chrysi& Kokkinos, Alexander& Tentolouris, Nicholas& Katsilambros, Nicholas L.. 2010. The Effect of Ingested Macronutrients on Postprandial Ghrelin Response : A Critical Review of Existing Literature Data. International Journal of Peptides،Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-492476
Modern Language Association (MLA)
Koliaki, Chrysi…[et al.]. The Effect of Ingested Macronutrients on Postprandial Ghrelin Response : A Critical Review of Existing Literature Data. International Journal of Peptides No. 2010 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-492476
American Medical Association (AMA)
Koliaki, Chrysi& Kokkinos, Alexander& Tentolouris, Nicholas& Katsilambros, Nicholas L.. The Effect of Ingested Macronutrients on Postprandial Ghrelin Response : A Critical Review of Existing Literature Data. International Journal of Peptides. 2010. Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-492476
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492476