On the Complexity of Electrostatic Suspension Stabilization of Functionalized Silica Nanoparticles for Biotargeting and Imaging Applications
Joint Authors
Bergman, Lotta
Rosenholm, Jessica
Öst, Anna-Brita
Kankaanpää, Pasi
Lindén, Mika
Duchanoy, Alain
Heino, Jyrki
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-04-07
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Civil Engineering
Abstract EN
Different means of attaching streptavidin to surface functionalized silica particles with a diameter of 240 nm were investigated with special focus on suspension stability for electrostatically stabilized suspensions.
The influence of two different fluorescent dyes covalently linked to the streptavidin on suspension stability was also studied.
The results clearly show that the stability of the suspensions is crucially dependent on all functional groups present on the surface.
The surface functions may either directly affect the effective surface charge if the functions contain charged groups, or indirectly by affecting the relative concentration of charged groups on the particle surface.
Poly(ethylene imine)-functionalized silica particles, where the polymer is grown by surface hyperbranching polymerization, are shown to be promising candidates for bioapplications, as the zeta-potential can remain strongly positive even under biologically relevant conditions.
American Psychological Association (APA)
Bergman, Lotta& Rosenholm, Jessica& Öst, Anna-Brita& Duchanoy, Alain& Kankaanpää, Pasi& Heino, Jyrki…[et al.]. 2008. On the Complexity of Electrostatic Suspension Stabilization of Functionalized Silica Nanoparticles for Biotargeting and Imaging Applications. Journal of Nanomaterials،Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-492537
Modern Language Association (MLA)
Bergman, Lotta…[et al.]. On the Complexity of Electrostatic Suspension Stabilization of Functionalized Silica Nanoparticles for Biotargeting and Imaging Applications. Journal of Nanomaterials No. 2008 (2008), pp.1-9.
https://search.emarefa.net/detail/BIM-492537
American Medical Association (AMA)
Bergman, Lotta& Rosenholm, Jessica& Öst, Anna-Brita& Duchanoy, Alain& Kankaanpää, Pasi& Heino, Jyrki…[et al.]. On the Complexity of Electrostatic Suspension Stabilization of Functionalized Silica Nanoparticles for Biotargeting and Imaging Applications. Journal of Nanomaterials. 2008. Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-492537
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492537