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A Case of Pemphigus Herpetiformis in a 12-Year-Old Male
Joint Authors
Akhdari, N.
Amal, S.
Ait Sab, I.
Hocar, O.
Hakkou, M.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-07
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Pharmacy, Health & Medical Sciences
Pharmacology
Abstract EN
Pemphigus herpetiformis (PH) is one of the less common forms of pemphigus.
PH in children is unreported.
We describe a case of a child who developed PH.
Observation.
A 12-year-old boy was seen at our department with erosive plaques, vesicles, and crusted cutaneous lesions associated with severe itching persisting for six months.
Histologic examination showed an intraepidermal bulla containing rare acantholytic epidermal cells with eosinophilic spongiosis.
Direct immunofluorescence demonstrated intercellular Ig G and C3 deposit.
The serum titer of antibodies against intercellular epidermal was 1/200 UI/l.
Diagnosis of PH was made, and treatment with Dapsone 2 mg/kg per day resulted in total clinical remission.
However, two months later, new vesicles reappeared and treatment was begun with prednisone at a dose of 2 mg/kg daily.
There was a very good response.
Discussion.
Childhood pemphigus herpetiformis is a rare disease, often initially misdiagnosed.
It must not be forgotten that the disease is a possible cause of erosive mucocutaneous disease in children.
American Psychological Association (APA)
Hocar, O.& Ait Sab, I.& Akhdari, N.& Hakkou, M.& Amal, S.. 2011. A Case of Pemphigus Herpetiformis in a 12-Year-Old Male. ISRN Pediatrics،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-492542
Modern Language Association (MLA)
Hocar, O.…[et al.]. A Case of Pemphigus Herpetiformis in a 12-Year-Old Male. ISRN Pediatrics No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-492542
American Medical Association (AMA)
Hocar, O.& Ait Sab, I.& Akhdari, N.& Hakkou, M.& Amal, S.. A Case of Pemphigus Herpetiformis in a 12-Year-Old Male. ISRN Pediatrics. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-492542
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492542