Strategies to Prevent Anthracycline-Related Congestive Heart Failure in Survivors of Childhood Cancer
Joint Authors
Gelehrter, Sarah K.
Armenian, Saro H.
Chow, Eric J.
Source
Cardiology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Cardiovascular complications are a leading cause of therapy-related morbidity and mortality in long-term survivors of childhood malignancy.
In fact, childhood cancer survivors are at a 15-fold risk of developing CHF compared to age-matched controls.
There is a strong dose-dependent association between anthracycline exposure and risk of CHF, and the incidence increases with longer followup.
Outcome following diagnosis of CHF is generally poor, with overall survival less than 50% at 5 years.
The growing number of childhood cancer survivors makes it imperative that strategies be developed to prevent symptomatic heart disease in this vulnerable population.
We present here an overview of the current state of knowledge regarding primary, secondary, and tertiary prevention strategies for childhood cancer survivors at high risk for CHF, drawing on lessons learned from prevention studies in nononcology populations as well as from the more limited experience in cancer survivors.
American Psychological Association (APA)
Armenian, Saro H.& Gelehrter, Sarah K.& Chow, Eric J.. 2012. Strategies to Prevent Anthracycline-Related Congestive Heart Failure in Survivors of Childhood Cancer. Cardiology Research and Practice،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-492618
Modern Language Association (MLA)
Armenian, Saro H.…[et al.]. Strategies to Prevent Anthracycline-Related Congestive Heart Failure in Survivors of Childhood Cancer. Cardiology Research and Practice No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-492618
American Medical Association (AMA)
Armenian, Saro H.& Gelehrter, Sarah K.& Chow, Eric J.. Strategies to Prevent Anthracycline-Related Congestive Heart Failure in Survivors of Childhood Cancer. Cardiology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-492618
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492618